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Bone metabolism Product details

 

Product name DPD (Quidel®)
 

Desoxypyridinolin-Crosslinks

Free DPD is measured

Cat-No. 8007
 

4822 DPD Control (Urine) Set of 4 x 0.5 ml (4 levels)
Average: 7, 21, 67, 172 nM

Range 3 - 300 nmol/l
Sensitivity 1.1 nmol/l
Incubation time 3 hours
Sample volume 50 µl (dilute 1:10)
Sample type

Urine, cell culture

Sample preparation

Use preservative-free first or second morning urine. Collect specimens before 10 a.m. Store samples refrigerated at 2-8°C for a maximum of 7 days or frozen at -20°C. Protect specimens from exposure to light.

Reference values
  Range
(nmol/mmol Cr)
Average
(nmol/mmol Cr)
Premenopausal women
(25 - 44 years)
3.0 - 7.4 5.0
men (25 - 55 years)  2.3 - 5.4 3.8


Reference values from children are available.

Species

Human, rat, mouse, rabbit, guinea pig, dog, porcine, sheep, cynomolgus macaque, bovine, horse, squirrel, baboon, rhesus macaque

Cross reaction

Negligible cross-reaction with DPD peptides and peptide bound pyridinoline.

Tests 96 Tests
Method ELISA
Product informations - Kit Instructions (pdf-File 202 kb)
- Animal reference Values (pdf-File 25 kb)
- Children reference Values (pdf-File 400 kb)
- Cross-reaction all species (pdf-File 71 kb)
- Cell culture (pdf-File 93 kb)
- Datasheet (pdf-File 131 kb)
- Bone & Cartilage Metabolism (pdf-File 2,480 kb)
Intended use

Quidel® DPD provides a quantitative measurement of the excretion of deoxypyridinoline (DPD) crosslinks as an indicator of bone resorption. Elevated levels of urinary DPD indicate elevated bone resorption in individuals. Measurement of DPD is intended as an aid for monitoring bone resorptional changes in postmenopausal women receiving hormonal or bisphosphonate anti resorptive therapies and in individuals diagnosed with osteoporosis.

Keywords product

Pyrilinks D,Dpd, ELISA, Desoxypyridinolin-Crosslinks, Type I collagen, Anti resorptive therapy, Bone resorption, Osteoporosis, Bone marker